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22LB R454B refrigerant cylinder front view
R454B refrigerant cylinder sealed valve detail
R454B refrigerant cylinder and product label
22LB R454B refrigerant cylinder packaging
R454B refrigerant cylinder safety label
R454B refrigerant cylinder rear view
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REFRINEXA / Refrigerants
R-454B 22LB Cylinder A2L Refrigerant

22LB R454B R-454B Freon Refrigerant Gas

A 22 lb cylinder of R-454B refrigerant intended for compatible air-conditioning and refrigeration equipment specifically designed and approved for R-454B.

Professional-grade HVAC supply
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Available to order
22 lb refrigerant cylinder with a tightly sealed valve.
For systems explicitly labeled and engineered for R-454B.
Available for delivery throughout the United States.
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22LB Net cylinder size
R-454B Refrigerant type
U.S. Delivery Ships nationwide

Why order from REFRINEXA?

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R Clear compatibility information
22LB

Practical cylinder size

A convenient supply format for qualified HVAC and refrigeration service work.

R-454B

Equipment-specific refrigerant

Designed for systems whose manufacturer documentation explicitly calls for R-454B.

A2L

Professional handling

A mildly flammable refrigerant that requires approved tools and trained handling.

USA

Nationwide availability

Available to order and ships throughout the United States.

HVAC technician servicing an air conditioning system
Professional HVAC supply

Made for compatible R-454B systems

R-454B is used in newer heating and cooling equipment engineered for this specific refrigerant. Always verify the equipment data plate and manufacturer documentation before charging or servicing a system.

  • Suitable only for equipment specifically approved for R-454B.
  • Use approved A2L recovery, charging and leak-detection equipment.
  • Do not mix R-454B with another refrigerant.
  • Charging and service should be completed by qualified personnel.
Product information

Clear specifications before you order

Review your equipment documentation and confirm the required refrigerant before purchasing.

Product type Refrigerant gas
Refrigerant designation R-454B
Cylinder size 22LB
Safety classification A2L – Mildly flammable
Container Single sealed cylinder
Compatible equipment Systems specified for R-454B
Application HVAC and refrigeration service
Availability United States
Technician working on a compatible outdoor HVAC unit
Correct system matching

Check compatibility before charging

Refrigerants are not interchangeable simply because they serve similar applications. R-454B should never be treated as a universal drop-in replacement. The unit label, service manual and manufacturer procedures determine the correct refrigerant.

  • Confirm “R-454B” on the equipment label or service documentation.
  • Follow the manufacturer’s specified charging method and charge amount.
  • Use components and tools rated for A2L refrigerants.
  • Observe all applicable ventilation, transport and storage rules.
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Cooling applications

Reliable supply for professional service needs

From residential comfort systems to commercial cooling environments, refrigerant selection must always follow the equipment manufacturer’s exact specification. Use this cylinder only where R-454B is clearly required.

Handling guidance

Store and handle responsibly

R-454B is classified as an A2L refrigerant. Proper equipment, training and storage practices are essential.

Keep upright

Store and transport the cylinder securely in an upright position.

Ventilated location

Keep the cylinder in a cool, dry and adequately ventilated area.

Avoid heat and ignition

Keep away from flames, sparks, excessive heat and incompatible materials.

Approved equipment

Use tools and components specifically rated for A2L refrigerant service.

Important: Refrigerant service should be performed by trained and properly equipped personnel. The purchaser is responsible for following all applicable laws, regulations and manufacturer instructions.
Questions & answers

R-454B product FAQ

What type of refrigerant is included?
This listing is for one 22 lb cylinder of R-454B refrigerant gas.
Can R-454B be used in any air-conditioning system?
No. Use it only in equipment specifically designed, labeled and approved for R-454B. Always check the unit data plate and manufacturer service documentation.
Is R-454B a direct replacement for R-410A or R-22?
No. R-454B is not a universal drop-in replacement. Never mix refrigerants or substitute one refrigerant for another without explicit equipment-manufacturer approval.
Does R-454B require special handling?
Yes. R-454B has an A2L safety classification and is considered mildly flammable. Approved A2L tools, ventilation and professional procedures are required.
Where is this product available?
This product is available and ships throughout the United States.
What should I check before ordering?
Confirm that your system requires R-454B, verify the required quantity and make sure the service technician has equipment approved for A2L refrigerants.

22LB R-454B Refrigerant Cylinder

Confirm compatibility with your equipment, then order securely from REFRINEXA.

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